Pronunciation: NA-te-GLYE-nide
Generic Name: Nateglinide
Brand Name: Starlix
Starlix is used for:
Lowering blood sugar levels in patients with type 2 diabetes. It used along with diet and exercise. It may also be used for other conditions as determined by your doctor.
Starlix is an antidiabetic agent. It works by causing insulin to be released from the pancreas. This helps to lower blood glucose levels.
Do NOT use Starlix if:
- you are allergic to any ingredient in Starlix
- you have type 1 diabetes
- you have a certain problem associated with diabetes (diabetic ketoacidosis)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Starlix:
Some medical conditions may interact with Starlix. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have adrenocortical, pituitary, liver, or kidney problems
- if you have a high fever, or poor health or nutrition
Some MEDICINES MAY INTERACT with Starlix. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amiodarone, beta-adrenergic blockers (eg, metoprolol), gemfibrozil, guanethidine, imidazoles (eg, ketoconazole), monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oxandrolone, or salicylates (eg, aspirin) because the risk of low blood sugar may be increased
- Corticosteroids (eg, prednisone), phenytoin, rifamycins (eg, rifampin), somatropin, St. John's wort, sympathomimetics (eg, pseudoephedrine), thiazides (eg, hydrochlorothiazide), or thyroid hormones (eg, levothyroxine) because they may decrease Starlix's effectiveness
- Somatostatin analogs (eg, octreotide) because they may decrease Starlix's effectiveness or increase the risk of low blood sugar
This may not be a complete list of all interactions that may occur. Ask your health care provider if Starlix may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Starlix:
Use Starlix as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Starlix by mouth 1 to 30 minutes before meals.
- If you skip a meal, you must also skip your scheduled dose to avoid the risk of low blood sugar levels (hypoglycemia).
- Talk to your doctor or other health care provider about what to do if you miss a dose of Starlix.
Ask your health care provider any questions you may have about how to use Starlix.
Important safety information:
- Starlix may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Starlix with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Follow the diet and exercise program given to you by your health care provider.
- Strenuous exercise, drinking alcohol, fever, infection, surgery, trauma, dieting, and skipping meals can affect your blood sugar levels.
- Carry an ID card at all times that says you have diabetes.
- Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take Starlix exactly as prescribed, tell your doctor.
- Starlix may cause low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.
- Tell your doctor or dentist that you take Starlix before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including fasting blood sugar levels and hemoglobin A1c levels, may be performed while you use Starlix. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Starlix with caution in the ELDERLY; they may be more sensitive to its effects.
- Starlix should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use Starlix if you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if Starlix is found in breast milk. Do not breast-feed while taking Starlix.
Possible side effects of Starlix:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Dizziness; flu-like symptoms (fever, chills, sore throat); joint pain; upper respiratory tract infection.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, stomach pain, unusual nausea or tiredness, yellowing of the skin or eyes); symptoms of low blood sugar (eg, anxiety, chills, fast heartbeat, headache, increased hunger, severe or persistent dizziness or drowsiness, tremors, unusual sweating, vision changes, weakness).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Starlix side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in vision; headache; increased hunger; loss of consciousness; nervousness; seizures; shakiness; sweating; tiredness.
Proper storage of Starlix:
Store Starlix at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container. Store away from heat, light, and moisture. Do not store in the bathroom. Keep Starlix out of the reach of children and away from pets.
General information:
- If you have any questions about Starlix, please talk with your doctor, pharmacist, or other health care provider.
- Starlix is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Starlix. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Starlix resources
- Starlix Side Effects (in more detail)
- Starlix Use in Pregnancy & Breastfeeding
- Drug Images
- Starlix Drug Interactions
- Starlix Support Group
- 0 Reviews for Starlix - Add your own review/rating
- Starlix Prescribing Information (FDA)
- Starlix Consumer Overview
- Starlix Monograph (AHFS DI)
- Starlix Advanced Consumer (Micromedex) - Includes Dosage Information
- Nateglinide Prescribing Information (FDA)
- Nateglinide Professional Patient Advice (Wolters Kluwer)
Compare Starlix with other medications
- Diabetes, Type 2
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