Free Articles Directory Montserrat: Prepulsid

Generic Name: cisapride (Oral route)

SIS-a-pride

Commonly used brand name(s):

In Canada

Novo-Cisapride

Prepulsid

Available Dosage Forms:

Suspension

Tablet

Therapeutic Class: Stimulant, Gastrointestinal

Uses For Prepulsid

Cisapride is a medicine that increases the movements or contractions of the stomach and intestines. It is used to treat symptoms such as heartburn caused by a backward flow of stomach acid into the esophagus.

Cisapride will only be available in the U.S. to certain patients who meet eligibility criteria from the manufacturer. Your doctor must enroll in a special program in order to prescribe this medicine for you. Cisapride is not available in Canada.

This medicine was available only with your doctor's prescription.

Janssen Pharmaceutica stopped marketing Propulsid® (cisapride) and has made it available only through an investigational limited access program .

Before Using Prepulsid

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Cisapride can cause serious side effects in any patient. Therefore, it is especially important that you discuss with the child's doctor the good that this medicine may do, as well as the risks of using it.

Geriatric

Elderly people are especially sensitive to the effects of cisapride. Cisapride stays in the body longer so the dose may be different than in younger people.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Acecainide

Acetophenazine

Ajmaline

Amiodarone

Amisulpride

Amitriptyline

Amoxapine

Amprenavir

Aprepitant

Aprindine

Arsenic Trioxide

Astemizole

Atazanavir

Azimilide

Bepridil

Bretylium

Chloral Hydrate

Chloroquine

Chlorpromazine

Clarithromycin

Clomipramine

Dalfopristin

Darunavir

Delavirdine

Desipramine

Diltiazem

Disopyramide

Dofetilide

Dolasetron

Dothiepin

Doxepin

Dronedarone

Droperidol

Efavirenz

Enflurane

Erythromycin

Ethopropazine

Flecainide

Fluconazole

Fluphenazine

Fluvoxamine

Fosamprenavir

Fosaprepitant

Foscarnet

Gatifloxacin

Gemifloxacin

Grepafloxacin

Halofantrine

Haloperidol

Halothane

Ibutilide

Imipramine

Indinavir

Isoflurane

Isradipine

Itraconazole

Ketoconazole

Levomethadyl

Lidoflazine

Lofepramine

Lorcainide

Maprotiline

Mefloquine

Mesoridazine

Methadone

Methotrimeprazine

Mibefradil

Moricizine

Moxifloxacin

Nefazodone

Nelfinavir

Nortriptyline

Octreotide

Opipramol

Pentamidine

Perphenazine

Pimozide

Pipotiazine

Pirmenol

Posaconazole

Prajmaline

Probucol

Procainamide

Prochlorperazine

Promazine

Promethazine

Propafenone

Propiomazine

Protriptyline

Quetiapine

Quinidine

Quinupristin

Ranolazine

Recainam

Risperidone

Ritonavir

Saquinavir

Sematilide

Sertindole

Sotalol

Sparfloxacin

Spiramycin

Sulfamethoxazole

Sultopride

Tedisamil

Telithromycin

Terfenadine

Terodiline

Thiethylperazine

Thioridazine

Tipranavir

Trifluoperazine

Triflupromazine

Trimeprazine

Trimethoprim

Trimipramine

Troleandomycin

Vasopressin

Voriconazole

Ziprasidone

Zolmitriptan

Zotepine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Iloperidone

Lapatinib

Lumefantrine

Nilotinib

Sunitinib

Tetrabenazine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acenocoumarol

Anisindione

Betel Nut

Cyclosporine

Dicumarol

Nevirapine

Phenindione

Phenprocoumon

Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco.

Grapefruit Juice

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

Proper Use of cisapride

This section provides information on the proper use of a number of products that contain cisapride. It may not be specific to Prepulsid. Please read with care.

Take this medicine 15 minutes before meals and at bedtime with a beverage, unless otherwise directed by your doctor.

Grapefruit and grapefruit juice may increase the effects of cisapride by increasing the amount of this medicine in the body. You should not eat grapefruit or drink grapefruit juice while you are taking this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and suspension):
- For heartburn caused by gastroesophageal reflux:
  - Adults and children 12 years of age and older—5 to 20 milligrams (mg) of cisapride two to four times a day. Cisapride should be taken fifteen minutes before meals and at bedtime.
  - Children up to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.15 to 0.3 mg of cisapride per kilogram (0.07 to 0.14 mg per pound) of body weight three to four times a day, fifteen minutes before meals.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Prepulsid

This medicine may cause your body to absorb alcohol more quickly than you normally would. Therefore, you may notice the effects sooner. Check with your doctor before drinking alcohol while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Prepulsid Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Blurred vision or other changes in vision

convulsions (seizures)

dizziness

fainting or feeling faint

fast or racing heartbeat

pounding or irregular heartbeat

swelling of face, hands, lower legs, and/or feet

unusual weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

Abdominal pain or cramping

constipation

diarrhea

drowsiness

dryness of mouth

headache

heartburn or indigestion

nausea

runny nose

tremor

unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

More Prepulsid resources

Prepulsid Side Effects (in more detail)
Prepulsid Use in Pregnancy & Breastfeeding
Prepulsid Drug Interactions
Prepulsid Support Group
1 Review for Prepulsid - Add your own review/rating

Compare Prepulsid with other medications

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Friday, 2 March 2012

Prepulsid